Segmental sandwich osteotomy of the posterior mandible in pre-implant surgery - A systematic review.

BACKGROUND: The rehabilitation of the atrophic posterior mandible with dental implants often requires bone augmentation procedures. The aim of the present study is the systematic review of the literature concerning the success rate of Segmental Sandwich Osteotomy (SSO) of the posterior mandible in pre-implant surgery. MATERIAL AND METHODS: Systematic review of all clinical cases and clinical studies of SSO of the posterior mandible in pre-implant surgery with a minimum follow-up of 6 months after implant loading was performed, based on specific inclusion and exclusion criteria. The search strategy involved searching the electronic databases of MEDLINE, EMBASE, COCHRANE LIBRARY, Clinical Trials (www.clinicaltrials.gov) and National Research Register (www.controlled-trials.com), supplemented by a manual search, in August 2015. In every study, the intervention characteristics and the outcome were recorded. RESULTS: Out of the 756 initial results, only 17 articles fulfilled the predetermined inclusion and exclusion criteria. They consisted of 9 retrospective case reports or series and 8 prospective randomized clinical trials. Overall, the studies included 174 patients. In these patients, 214 SSO augmentation procedures were performed in the posterior mandible and 444 implants were placed. The follow-up period after implant loading ranged between 8 months and 5.5 years. The success rate of SSO ranged between 90% and 100%. The implant survival during the follow-up period ranged between 90.9% and 100%. CONCLUSIONS: Segmental Sandwich Osteotomy should be considered as a well documented technique for the rehabilitation of the atrophic posterior mandible, with long-term postsurgical follow-up. The success rates are very high, as well as the survival of the dental implants placed in the augmented area.

Oro-facial tumours and tumour-like lesions in Greek children and adolescents: an 11-year retrospective study.

OBJECTIVE: To determine the epidemiology, histological diagnosis and treatment outcome of oro-facial tumours and tumour-like lesions in Greek children and adolescents. MATERIAL AND METHODS: The medical records of patients with oro-facial lesions who presented at the Department of Oral and Maxillofacial Surgery at "A. & P. Kyriakou" Children's Hospital from 2000 to 2010 were reviewed. Data was analyzed in relation to age, gender, location, histology, treatment choice and outcome. RESULTS: Two hundred and eleven oro-facial lesions were identified. Age ranged from 14 days to 15 years (mean 8 years); the male-to-female ratio was 1.09: 1; 90.05% of the lesions were benign and 9.95% malignant. Vascular anomalies were the most common benign lesion (22.1%) and rhabdomyosarcoma was the most prevalent malignancy (28.57%). One hundred and ten lesions (52.1%) involved soft tissue, most commonly the tongue and 96 cases (45.5%), involved hard tissue, most frequently the mandible; 5 lesions (2.4%) involved both hard and soft tissue. Surgery was performed under general anaesthesia in 198 cases (93.84%). Some malignant lesions were treated with chemotherapy and/or radiotherapy. CONCLUSIONS: Oro-facial tumours and tumour-like lesions are not uncommon in the Greek paediatric population; although most frequently benign, these may cause considerable morbidity. As such early diagnosis and treatment are imperative.

Iliac crest morbidity following maxillofacial bone grafting in children: a clinical and radiographic prospective study.

UNLABELLED: Bone harvesting from the anterior iliac crest is commonly performed for grafting of maxillofacial defects. PURPOSE: To evaluate the morbidity of the procedure in children and adolescents with clefts or maxillofacial defects after tumour removal. PATIENTS AND METHODS: Between 2001 and 2008 36 consecutive patients who underwent iliac crest bone grafting using the trap-door technique were evaluated 6 months to 7 years postoperatively. Objective and subjective findings regarding the donor site mostly but also the recipient site were assessed by a standardized physical and radiological examination and a questionnaire. The donor site scar, neurosensory and motility function were evaluated clinically and osseous healing was investigated through radiographic examination of the ilium. RESULTS: All respondent patients (29 out of the 36) tolerated the procedure well without major complications. Minor complications (mild pain and limp) were of short duration. No growth disturbances or contour deficits at the donor site were noted. No neurosensory or functional irregularities were detected. The donor site scar was considered aesthetically acceptable and most of the patients were satisfied with the functional outcome at the recipient site. CONCLUSIONS: Bone harvesting from the anterior iliac crest was found to be a safe and reliable procedure for maxillofacial bone grafting in paediatric patients. No complications were encountered, the morbidity was minimal and the aesthetic outcome was good.

Treatment of macroglossia in a child with Weaver syndrome.

Weaver syndrome is a rare disorder, characterized by accelerated growth, advanced osseous maturation and distinct craniofacial features. Macroglossia and hypothyroidism are seldom mentioned in the literature as clinical findings associated with the syndrome. This paper describes a patient with Weaver syndrome, referred for consultation and treatment of macroglossia, who also suffered from congenital hypothyroidism. This is the first reported case of Weaver syndrome treated with partial glossectomy (tongue reduction). The paper describes the clinical findings of the syndrome, emphasizing the difficulty in identifying it, the indications for partial glossectomy and the authors' recommended operative technique.

Case report: desmoplastic fibroma of the mandible in a child presenting with TMJ dysfunction.

BACKGROUND: Desmoplastic fibroma of bone is a rare intraosseous benign but locally aggressive tumor of connective tissue origin. The lesion may affect the metaphyses of the long bones but it may also involve the skull bones and more specifically the mandible, with most lesions appearing in the ramus-angle area. Treatment is surgical although additional chemotherapy or radiation has been applied. CASE REPORT: A 10-year-old boy initially presented with restriction and deviation of mouth opening. Clinical and radiological examination revealed a tumor-like lesion of the mandible extending into the soft tissues, which on biopsy proved to be a desmoplastic fibroma. TREATMENT: The surgical treatment included peripheral ostectomy of the mandible, via an intraoral approach, for the removal of the lesion and restoration of the bone defect with an iliac bone autograft. FOLLOW-UP: The high recurrence rate of this type of lesion, demands a strict follow-up schedule. In the case presented, 5 years post-operatively, there are no signs of local recurrence. CONCLUSION: Changes in mouth opening when not attributed to obvious reasons, such as trauma, should make a dentist suspicious and lead to further investigation. In the case presented, a central lesion was revealed in the radiograph and the patient was referred and treated early. Extended surgical removal of the tumor, with wide margins, proved to be the appropriate treatment.

Use of membrane and bone grafts in the reconstruction of orbital fractures.

OBJECTIVE: To present and analyze the clinical results derived from the use of different grafts for the reconstruction of orbital defects during a 10-year period. STUDY DESIGN: Fifty-five fracture cases with orbital bony defect, requiring a graft, are presented. The surgical treatment includes the reconstruction of the fracture (osteosynthesis) and the repair of the remaining bone defect by graft, with the type of graft dependent on the size of the defect. For minor defects membranes were used (lyophilized dura or alloplastic dura mater), whereas major defects were repaired with bone grafts (autografts, heterografts, or bone substitute material). All patients have been regularly evaluated for at least one year postoperatively. RESULTS: All grafts were well tolerated by the patients. Diplopia subsided in all but 5 cases, motility disturbance was fully repaired in all but 3 cases. Esthetics were improved in cases with severe bone defect. CONCLUSION: The wide variety of grafts available allows successful reconstruction of all types of orbital bony defects. The clinician should be able to use different types of grafts depending on the type and size of the defect.

Miniplate osteosynthesis for fractures of the edentulous mandible: a clinical study 1989-96.

Our 8 years experience of treating fractures of the edentulous mandible by miniplate osteosynthesis, is discussed. Forty patients (31 men and 9 women) aged 37 to 86 years (mean: 64.6 years, SD: +/- 14.07) with 67 fracture sites were treated. The surgical approach was mainly intraoral (37 out of 40 patients) without the use of intermaxillary fixation. The postoperative clinical and radiological findings are reported and discussed. The advantages of the method are of great importance since immediate postoperative opening of the mouth is permitted, as the fractured bones are anatomically stabilized by means of titanium miniplates and screws. Our results were felt to be satisfactory, with a reoperation rate of only 3.9% (two out of 51 operated fracture sites, 16 condylar fractures were treated conservatively). This allows us to propose intraoral miniplate osteosynthesis as a routine method of treatment in cases of edentulous mandibular fractures which are mainly seen in elderly people.

Blood supply to the oral and maxillofacial tissues following radiation therapy: a prospective ultrasonographic study.

In this prospective clinical study of the early radiation effects on blood supply to the mouth and face, 44 patients (31 men-13 women, mean age 63.4 yrs) with oral tumors underwent surgery and adjuvant postoperative radiotherapy with conventional fractionation (mean dose at the neck approximately equal to 50 Gy). Blood flow parameters 1 cm below the bifurcation of the common carotid artery (mean velocity time averaged, lumen diameter, resistivity index-RI) as well as perivascular reaction, were recorded on Color Doppler Imaging video tapes in a series of five consecutive examinations up to six months postirradiation. There were no statistically significant changes shown between the initial and follow-up examinations for any of the parameters investigated. There was no difference in blood flow between the ipsilateral (operated-irradiated) and contralateral side of the neck. Results did not seem to correlate with known vascular disease risk factors such as sex, arterial pressure, cholesterol levels, smoking and diabetes. After the effect of age was controlled, flow measurements remained statistically stable. Radiation dosage did not appear to influence carotid flow parameters. Perivascular reaction had the highest peak immediately postirradiation but regressed with time. This study suggests that therapeutic radiation of the neck at this dose level may not have important effects on the maxillofacial region blood supply for approximately eight months postoperatively; however, these patients should be closely evaluated for symptoms or signs of carotid artery lesions on a long-term basis.

[Central giant cell granuloma of the maxilla]. / kentriko gigantokyttariko kokkioma tes ano gnathou.

We report the experience of the clinical, histologic and radiologic features of a giant cell granuloma of the maxilla of severe growth. The removal of the lesion led to a large defect of the maxilla with oroantral fistula, which was immediately repaired by the use of the temporalis muscle flap. A four year follow-up period revealed no evidence of recurrence as well as excellent aesthetic and functional results. Further diagnostic and therapeutic problems are discussed in relation with recent literature.

[Solitary plasmacytoma of the mandible]. / Moneres plasmatokyttoma tes kato gnathou.

Solitary plasmacytoma of the bone is believed to be manifestation of the spectrum of diseases presented by the term plasma cell neoplasms and the lesion rarely involves the jaws. A case of solitary plasmacytoma of the mandible is presented, the diagnostic problem is posed and the method of treatment by peripheral osteotomy and radiotherapy discussed.

[Primary melanoma of the oral cavity]. / Protopathes melanoma ste stomatike koiloteta.

Melanoma most often develops in the skin; usually at the site of a preexisting nevus. It is quite rare in the oral cavity and the maxilla is the most common location there. It appears that males between 60 and 70 years old are affected more often than females. The etiology is unknown. However the melachromatic nevus and the color of the skin are considered predisposing factors. Based on clinical and histologic criteria it is classified in three categories. Unfortunately the frequency of the occurrence of each category into the mouth separately, is inversely proportional to the prognosis. The 5 year survival rate of intraoral melanoma does not exceed 5-9%. The treatment of melanoma is surgical and comprises radical excision of the lesion and radical neck dissection. Radiotherapy and chemotherapy do not seem to contribute to the treatment. We present our experience of two patients with melanoma of the maxilla. In one case submandibular lymphadenopathy had already been established and a radical neck dissection was performed. In the other case subtotal maxillectomy was performed with intraoral approach.

Anaerobic bacteria in jaw cysts.

The bacterial flora of the fluid content of 54 cysts of the jaws with a history suggestive of infection were studied. Forty-seven of these cysts were subsequently considered to be infected and from 78.6% of these, positive bacterial cultures were developed. Of the bacterial strains 89.2% were anaerobes and only 10.8% were pure aerobes or facultative anaerobes. Microorganisms isolated from each specimen ranged from 1 to 4 bacterial species. Gram positive anaerobic cocci revealed to be the most frequent bacterial group (36.9%), followed by Gram negative anaerobic rods (29.8%), Gram positive aerobic cocci being the third most common group of the isolates (19.0%). Antibiotic sensitivity tests of the isolated anaerobic cocci to a group of nine antibiotics revealed chloramphenicol and minocycline as the most effective. All anaerobic rods tested, were sensitive to metronidazole.